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mutations, lost their detrimental outcome in clients taken care of with VO. The only factor that remained predictive of the shorter development-absolutely free survival in this cohort of patients was TP53
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) and integrated into these prognostic techniques, but none of these tries succeeded in turning into regular of care.ninety four–ninety six In fact, the Intercontinental Workshop on CLL (iwCLL) tips only recommend analyzing the IGHV position and existence/absence of TP53 aberrations in regime observe.
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mutations and complex kar yotype. It follows a linear evolution through the CLL clone throughout the recurrent acquisition of CDKN2A
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